Research Histopathology Scientist

Research Histopathology Scientist

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.

That’s what makes us Roche.

In Roche’s Pharmaceutical Research and Early Development organization (pRED ), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

360 Labs Initiative at a Glance

The 360 Labs are a new capability that is currently being built up within the Pharmaceutical Research and Early Development organization (pRED ). The primary mission of this effort is to provide greater access and support for the use of cutting-edge biomedical research technologies by scientists across our discovery portfolio.

The 360 Labs will deliver core scientific technologies, expertise and enabling activities, as well as facilitate knowledge sharing in close collaboration with our therapeutic areas and functions. Our ambition is to bring to life a thriving workplace environment, where your collaborative mindset is as valued as your professional expertise. Our goal is to act as a highly integrated ecosystem, supporting research and development, working collaboratively, and focused on fostering excellence and sustainability. Together, these efforts will serve to increase the speed, enhance the robustness and improve the sustainability of our exploratory research and early discovery activities.

Job Mission and Impact

The Research Histopathology Core Technology Platform in the 360 Labs Initiative is seeking to add to its team an experienced, highly-motivated and collaborative histopathology scientist to provide histology services, with a focus on multiplexed IHC and IF assays. The successful candidate will have a strong background in developing, implementing and running (ultra-) high-multiplex immunostaining approaches end-to-end, and has worked with the latest technologies in the field. You will work as a part of a matrix team and collaborate closely with experts within and outside the 360 Labs Initiative to collaboratively advance exploratory research and early drug discovery programs, and participate in the implementation and growth of the Research Histopathology Platform within the pRED organization.

Your Role and Responsibilities

• Be responsible for the planning design and execution of specialty histological workflows, with a focus on implementing and optimizing both routine, and custom multiplexed staining approaches, including immunohistochemistry (IHC), in situ hybridization (ISH), immunofluorescence (IF) and digital pathology techniques such as whole slide scanning as well as other imaging technologies.

• Ensure the continued production, and reliability of high-quality research data by performing regular quality control and troubleshooting of histological instrumentation, and maintain accountability for the preparation of reports, presentation and discussion of data with key stakeholders.

• Embrace a continuous learning mindset by actively engaging with the scientific literature to stay abreast of emergent technologies/approaches in the histopathology field.

Your Profile

• A MS degree in biology, chemistry, or a related field, or a PhD degree with respectively 8 years or 5 years of professional experience focused on (ultra-) high-multiplexed tissue analysis either in an academic setting and / or the pharmaceutical industry / biotech sector.

• Exceptional competency with the histological preparation of mammalian tissues, including fixation, embedding, sectioning, staining and image acquisition with respect to multiplexing workflows, with high theoretical and hands-on knowledge of chemical and biological staining techniques.

• Extensive hands-on experience in implementing, optimizing and executing both routine and custom-designed assays with (ultra-) high-plex multiplexing devices, such as the Akoya Phenocycler or similar in a rigorous and reproducible manner..

In addition to your professional expertise and critical technical skills we are looking for candidates who:

• Are resourceful and flexible in problem solving, have excellent organizational skills, and are able to work as agile matrix leads with a sense of urgency in a fair, open and collaborative manner, ensuring that everyone has the required information at all times;

• Can think outside the box and work in diverse, multicultural, global teams, with a demonstrated ability to implement new ideas in fast-paced research environments

• Bring excellent written communication and presentation skills with a high fluency in English.

Your Location

This position is based in Basel.

Our commitment

Roche commits to recognizing talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career.

We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.