PhD Internship in cellular neuroscience - Tauopathy

PhD Internship in cellular neuroscience - Tauopathy

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

Your department and team

The Neural Signaling section within the Neuroscience and Rare Disease department is located in Basel. The overarching goal of the Neural Signaling Section is to move forward drug discovery projects, from target assessment to early clinical phase, in the therapeutic area of neurodegenerative diseases.

You will have the opportunity to collaborate within the department as well as with labs in the newly established Institute of human biology, consisting of scientists, research associates, PhD students and postdocs. The goal of this project is to study the mechanism of spreading of disease pathology in different neurodegenerative diseases.

Your tasks and responsibilities:

• You will perform laboratory activities such as iPSC neurons, transdifferentiated neurons maintenance, treatment and biochemical experimentation

• You will prepare samples and, in close collaboration with other technical experts, you will perform protein analysis

• You will implement new assays (transdifferentiation of neurons from fibroblasts) or optimize existing protocols based on literature search to meet the needs of the project

• You will perform immunostaining and perform confocal microscopy and high content imaging

• You will prepare data, analyze, interpret and present the data in the lab meetings

Your profile:

• You are currently enrolled at university as a PhD student (preferably at the end of your PhD)

• You are excited about performing laboratory experiments, learning techniques and motivated to perform research on cellular neuroscience

• You have hands-on experience on iPSC neurons, transdifferentiation preparation and/or iPSC maintenance (neurons and microglia), immunostaining, confocal microscopy, experience working on high content imaging & data processing and protein biochemistry such as western blot, immunoprecipitation and AlphaLISA etc

• You have the ability to design, perform and report the experimental data in high quality

• Fluency in English (written and spoken)

Your Advantages:

• Flexible working hours & attractive compensation package

• Access to world-class research facilities

• Guidance from expert scientists in learning & performing new techniques

• Possibility to contribute to publication

• Strong scope for networking with a large pool of scientists

Your Application:

Please upload your curriculum vitae specific to this position.

The internship will take place in Basel and is full-time.

The preferred start date of the internship is from August 2024 or according to agreement for a duration of 12 months.

Due to regulations, non-EU/non-EFTA citizens need to provide a certificate of enrollment and a certificate from the university stating that an internship is mandatory and stating the length of it.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.