Principal Scientist, Formulations

Johnson and Johnson is recruiting for a Principal Scientist, Formulations in Drug Product Development & Delivery to be located in Malvern, PA.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.

For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.

We know that the success of our business – and our ability to deliver meaningful solutions – depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.

At Johnson & Johnson, we all belong.

The Principal Scientist in the Drug Product Development & Delivery will be a lab-based role with expertise in protein science and support formulation development. The candidate will be an experienced individual contributor able to manage or contribute to scientific projects, programs, and processes. They will be responsible for the design and execution of experimental studies in pre-formulation, formulation and biophysical characterization of therapeutic proteins or other biologics including monoclonal antibodies (mAbs), multi-specifics, fusion proteins, and mixed conjugates. This includes development and optimization of the technical operations associated with liquid and lyophilized biologics development, diluent compatibility/administration relevant studies and stability campaigns.

Key Responsibilities:

• Design, complete, analyze, and document studies to develop and optimize formulations for biologic therapeutics. Studies include, but are not limited to, biophysical characterization, stability, composition selection, robustness, and development of administration protocols.


• Plan, conduct, evaluate, and record studies to support formulation selection and manufacturing unit operations including stability and excipient selection, freeze/thaw, and mixing.


• Design, complete, analyze, and document compatibility studies to support administration of biologic therapeutics.


• Clearly and effectively communicates, plans, results and decisions to key partners and broader team.


• Accurately interpret complex datasets and effectively communicate impact through formal and informal disclosures.


• Develop technologies and use new developments in emerging fields to improve processes, formulations, drug delivery strategies and generate innovative research ideas.