Laboratory Technician, in vivo (m/f/d, 100%)

NBE Therapeutics is a subsidiary of the Boehringer Ingelheim group: a perfect symbiosis between a rapidly growing biotechnology company and an already well established big pharma. We are located in Basel, a Swiss city on the river Rhine, known for being an important center of chemical and pharmaceutical industries but also renowned for its versatile cultural aspects – a great place to live and work. Our Research Team is committed to the development of next generation antibody drug conjugates for the treatment of cancer. We are looking for a highly motivated:

Laboratory Technician, in vivo (m/f/d, 100%)

Job Description

You will provide technical support in the evaluation of novel monoclonal antibodies and antibody drug conjugates (ADCs) in relevant mouse tumor models. As the team is still expanding, we are looking for a skilled and smart individual, who would like to work in a small team and learn/apply a broad range of techniques, in a dynamic environment where everybody’s performance has a direct influence on the success of the company.

Your tasks

• Perform in vivo experimental models of cancer in mice, including:
• Delivery of drug compounds and cells using various routes of administration (IV, PO, SC, IV, IP)
• Assessment of animal health throughout the study (health checks, clinical observations)
• Periodic measurements of bodyweights and tumors
• Harvest and preparation of tumor samples
• Ex vivo processing of in vivo material (e.g. with gentleMACS dissociator)
• Development and validation of new animal models, and ex-vivo and in-vitro assays according to the need of the department
• Skilled in basic in vitro techniques such as FACS, ELISA, Western-Blot, cell culture assays
• Independent planning, execution documentation of experiments and interpretation of results
• Review relevant literature to optimize experimental methods, stimulate new ideas and develop new assays for experimental studies
• Presentation of results within a multidisciplinary team environment
• Contribute to the general lab infrastructure, including ordering of consumables, and coordinating with colleagues the workflow, organization, maintenance, and function of lab resource

Your Profile

• Technical Diploma, B.Sc. or M.Sc. in Biology with certified training in animal work. Please note that candidates with a PhD degree are not suitable for the responsibilities of this position, thus their application will NOT be considered.
• Work experience and knowledge of preclinical in vivo models
• Officially recognized as animal experimenter (LTK1 or equivalent) by the Federal Veterinary Office
• Show technical expertise in all aspects of in vivo pharmacology (animal handling, substance application by various routs, blood sampling)
• Practical background in different in vitro techniques (FACS, ELISA, primary cell culture handling, SDS-PAGE, Western blot)
• Flexible person and keen to learn new skills and techniques
• Ability to work independently, flexibility with regard to working-hours and ability to accommodate changing priorities, timelines or tasks
• Good oral and written communication skills in English; additional knowledge of German preferred
• Well trained in computer programs: Excel, Power Point, Word, GraphPad Prism, FlowJo

What we offer

• Exciting opportunities for development and professional growth within our dynamic organization
• An opportunity to make a difference on the way to safe peoples life
• An innovative and open culture in a diverse and young environment

Who We Are and Our Culture

NBE-Therapeutics is an equal opportunity employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment, which benefits our employees, patients and communities.

In January 2021, NBE-Therapeutics joined as a subsidiary specialized in ADCs, the Boehringer Ingelheim group, which focuses on innovative medicines for people and animals since more than 130 years. Boehringer Ingelheim is one of the pharmaceutical industry’s top 20 companies and to this day remains family-owned. Day by day, more than 53’000 employees create value through innovation for the three business areas human pharmaceuticals, animal health and biopharmaceutical contract manufacturing. In 2023, Boehringer Ingelheim achieved a total revenue of nearly 25.6 billion euros. R&D investments, exceeding 5.8 billion euros, corresponded to 22.5% of net sales.

We look forward to receiving your application, including a motivation letter.

Please, send your documents to E-Mail schreiben referring to job-opening: Ref241216