Research Associate Discovery Oncology Target & Disease Biology Group

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

This position is located within our Target and Disease Biology Group within the Oncology Discovery organization dedicated to the discovery and development of novel cancer therapeutics within key tumor types (CRC, Lung, Breast). We collaborate closely with functions in Therapeutic Modalities, Pharmaceutical Science as well as within the oncology therapeutic area to translate hypotheses into innovative Therapeutics. This team also interfaces with the newly established Institute for Human Biology (IHB).

The Opportunity

As a Research Associate Discovery Oncology Target & Disease Group, you will address fundamental scientific questions, be responsible for the design and execution of experimental work, and conduct data analysis.

• Proficient in tissue culture and molecular and cell biology/ immunology methods including RNAi, qRT-PCR, stable cell line generation, genetic editing, proliferation / cell viability assays, western blotting, ELISA, multiplex assays and analyses and imaging methods including Incucyte.

• Experienced in Isolation, culture and maintenance of primary immune cells.

• Expertise in multicolor flow cytometry and in a range of cell based and functional in vitro assays .

• Experienced in cell specific proteomic labelling.

• Able to coordinate and manage multiple orthogonal studies and enthusiastically share knowledge through collaboration with other scientists and associates inside and outside the group.

• Present findings at internal meetings and maintain accurate electronic records.

• Enjoy working flexibly and embrace change.

• Manage interns and/or apprentices.

Who you are

​BSc/MSc in a life science discipline or completed Roche apprenticeship, at least 2 years of experience in a biomedical research laboratory (prior experience in the pharmaceutical industry desired), routinely conducted cell culture and proficient in a wide range of molecular biological and cellular methods, desired within the disease areas of focus (CRC, Lung, Breast). Prior experience with cell specific labelling approaches , 3D culture systems, Genetic editing and flow cytometry (desired). Experience in Mode of Action analysis or functional screening of drug candidates or target assessment compound screening.

• Strong interest in testing novel target hypotheses and establishing new assays to further enhance our disease biology understanding (desired). Passion to explore novel technologies /continue to build state-of-the-art tools (desired).

• Proficient with standard lab equipment and IT tools and capable of conducting and documenting original research independently. Familiar with Bioinformatic tools ( preferred ). With more in depth experience and capabilities, qualify for increased responsibilities and higher seniority level.

• collaborative team player, eager to learn, adapt and maintain a positive attitude, enjoy working in a high pace and flexible environment.

• excellent oral and written communication skills in English

Application deadline: 24 November 2024

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more .

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.