Biophysical characterization and stability studies Scientist at Numab Therapeutics AG
Publication date:
20 November 2024Workload:
100%Contract type:
Unlimited employment- Place of work:Zurich
Numab Therapeutics AG is an expanding, clinical stage Swiss biotech company based in Horgen, canton of Zürich. The company is focused on the discovery and development of innovative, antibody fragment-based therapeutics with a focus on inflammation and immuno-oncology. With our breakthrough antibody-discovery and multi-specifics engineering platform, we engage in proprietary projects as well as collaborative research on behalf of partners in the pharmaceutical industry. To develop Numab's innovative proprietary therapeutic pipeline we are looking for a highly motivated and experienced individual for a role as Research Associate within our Formulation and Analytics team.
Research Associate Formulation and Analytics 100% In this multi-faceted position, you will contribute to driving Numab's projects towards development and the clinical stages. You will be responsible for the biophysical characterization and stability investigations of our multispecific antibody-derived therapeutic proteins by applying methods from a variety of disciplines. Your Responsibilities:
Research Associate Formulation and Analytics 100% In this multi-faceted position, you will contribute to driving Numab's projects towards development and the clinical stages. You will be responsible for the biophysical characterization and stability investigations of our multispecific antibody-derived therapeutic proteins by applying methods from a variety of disciplines. Your Responsibilities:
- Biophysical characterization and stability studies of antibody-derived proteins
- Generation of high-quality data in biophysical and analytical assays to support Numab's discovery and development projects
- Critical review and interpretation of data to support the generation of developability profiles or lead formulation development
- Contribution to technology development projects and continuous improvement of processes (e.g. data analysis and automation)
- Planning, execution, analysis and presentation of experiments within team meetings and company presentations
- Work closely with team members to outline next steps and help to drive the projects to completion
- General organization of the laboratories, evaluation and acquisition of equipment and consumables
- Completed apprenticeship as laboratory technician with several years of experience or a higher education in biology, (bio-)chemistry or pharmaceutical sciences, preferably with industry experience in recombinant protein/antibody characterization and analytics
- Experience in stability indicating biophysical assays (e.g. self-association, hydrophobicy)
- Professional experience in analytical methods (e.g. SE-HPLC, CEX-HPLC, cGE)
- Experience in lab automation is a plus
- Good understanding of protein biochemistry
- Initiative, problem solving skills, self-motivation and curiosity
- Highly accurate and team-oriented working style paired with a high sense of quality
- Ability to work on diverse tasks independently
- Refined computer user skills (Windows, MS Office) and excellent communication skills
- A diverse field of activities in a dynamic team with an inspiring, entrepreneurial atmosphere
- Flat hierarchies and short decision-making paths
- The opportunity to take responsibility, help shaping and implementing solutions
- Employment conditions in line with the market, superior pension plan, flexible working time model, and opportunities for further personal development
- Performance-based bonus and participation in the employee stock option plan
- Several fun team events throughout the year
- A workplace near the city of Zurich overseeing the lake
