Scientist Formulation Development 100%
Key information
- Publication date:25 April 2025
- Workload:100%
- Contract type:Unlimited employment
- Place of work:Bachtobelstrasse, 8810 Horgen
In this diverse and impactful role, you will be at the forefront of driving Numab’s lead candidates from research into development and clinical stages. As a key member of our team, you’ll be responsible for developing robust liquid and lyophilized formulations of our multi-specific antibody-based therapeutics.
- Lead developability profiling of our biologics to ensure their suitability for clinical development
- Design and execute formulation studies – with a focus on parenteral liquid formulations – using statistical approaches such as Design of Experiments (DoE)
- Analyze formulation stability using a range of analytical methods including SE-HPLC, CEX-HPLC, cGE and others
- Drive early-phase biophysical screening – enhancing throughput while minimizing material use, and exploring new analytical technologies
- Interpret and present scientific data to internal teams and external stakeholders, proposing clear next steps for project progression
- Collaborate cross-functionally with team members to accelerate development and ensure timely project delivery
- Support lab operations – including the organization, evaluation, and procurement of equipment and consumables
- Completed MSc or PhD in biochemistry, biophysics or pharmaceutical sciences with industry experience in the field of biophysical assessment and/or development of liquid parenteral formulations of biologics
- Theoretical and practical expertise in evaluating protein biophysics and stability, such as colloidal, interfacial, and chemical stability to withing developability assessment and formulation development
- Experience in (high concentration) liquid formulation development of biologics and good understanding of relevant analytical methods to monitor stability, e.g. SE-HPLC, CEX-HPLC and cGE
- Professional experience in high throughput screens including the use of DoE
- Expertise in advanced data evaluation and analysis
- Initiative, problem solving skills, self-motivation and curiosity
- Highly accurate and team-oriented working style paired with a high sense of quality
- Excellent documentation, reporting and communication skills in English
- A diverse field of activities in a dynamic team with an inspiring, entrepreneurial atmosphere
- Flat hierarchies and short decision-making paths
- The opportunity to take responsibility, help shaping and implementing solutions
- Employment conditions in line with the market, superior pension plan, flexible working time model, and opportunities for further personal development
- Performance-based bonus and participation in the employee stock option plan
- Several fun team events throughout the year
- A workplace near the city of Zurich, overlooking the lake
Numab Therapeutics AG is an expanding, Swiss biotech company based in Horgen, canton of Zürich. The company is focused on the discovery and development of innovative, antibody fragment-based therapeutics with a focus on inflammation and immuno-oncology. With our breakthrough antibody-discovery and multi-specifics engineering platform, we engage in proprietary projects as well as collaborative research on behalf of partners in the pharmaceutical industry.
