Research Associate in Cardiovascular and Metabolic Diseases, in vitro
Publication date:
24 December 2024Workload:
100%- Place of work:Basel
Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.
The Position
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.
That’s what makes us Roche.
In Roche’s Pharmaceutical Research and Early Development organization (pRED ), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
We are seeking a motivated and detail-oriented Research Associate to join our Cardiovascular and Metabolic Diseases (CVM) department. You will play a crucial role in advancing our understanding of disease mechanisms and supporting early drug discovery. This position offers a unique opportunity to contribute to groundbreaking research while growing within a collaborative, dynamic and fast-paced environment.
The opporunity
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Conduct molecular biology techniques such as RNA isolation, qPCR, and protein quantification for mechanistic and functional studies.
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Perform in vitro assays, including Seahorse metabolic flux analysis, to evaluate mitochondrial respiration, glycolysis, and cellular bioenergetics.
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Isolate and culture adipocytes from human and animal tissues, optimizing protocols for primary cell isolation and maintenance.
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Execute fat and lipid analysis measurements, including lipid profiling, fluorescent lipid staining (e.g., BODIPY), and cholesterol quantification.
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Perform advanced cellular and biochemical techniques, such as flow cytometry for glucose uptake, immunocytochemistry, and ELISA for biomarker quantification.
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Analyze experimental data with statistical tools, preparing high-quality reports and presentations to communicate findings effectively.
Who you are:
You are someone who takes charge of your own development, thriving on teamwork, diligence, and efficiency. You are proactive, skilled at organizing multiple tasks, and committed to delivering high-quality results. A multicultural environment energizes you, and as a fast learner, you actively contribute to enhancing the quality of outcomes.
Requirements:
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You hold a Bachelor’s or Master’s degree in biology, biochemistry, or a related field, or have completed vocational training in biology. A minimum of 3 years in a research laboratory setting is required.
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You are proficient in cell culture, molecular biology, and biochemical techniques and are familiar with metabolic and cardiovascular disease models
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You have strong organizational skills, allowing you to multitask and prioritize effectively in dynamic environments, while thriving in agile matrix teams and contributing to shared goals.
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You communicate effectively in English, both in writing and orally
Your Location
This position is located in Basel, Switzerland.
Our commitment
Roche commits to recognising talent and aptitude. We prioritise encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career.
We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.
Who we are
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more .
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.
Contact
F. Hoffmann-La Roche AG