Senior Principal Scientist, Immunotoxicology
Veröffentlicht:
20 September 2024Pensum:
100%Vertrag:
Festanstellung- Arbeitsort:La Jolla
Johnson and Johnson is currently seeking a n Senior Principal Scientist, Immunotoxicology located onsite in La Jolla, CA.
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.
For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world’s most pressing healthcare challenges.
We know that the success of our business – and our ability to deliver meaningful solutions – depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.
At Johnson & Johnson, we all belong.
An exciting scientific leadership opportunity is open in the Immunotoxicology group within Preclinical Sciences and Translational Safety’s Pathobiology Organization at Johnson & Johnson for a highly skilled and critically thinking scientific leader that works exceptionally well in a fast-paced, collaborative team environment.
Primary responsibilities:
- Support portfolio progression of new therapeutics across therapeutic areas and multiple drug modalities (e.g. biologics, small molecules, oligonucleotides, gene therapy, cell therapy, and peptides) by evaluating and characterizing potential and observed immunotoxicological risks and immunopharmacological mechanisms.
- Make recommendations to drug discovery and development teams and communicate experimental rationale and scientific strategies to decipher/predict mechanisms of potential safety signals on the immune system.
- Independently lead investigative strategies/studies to explore mechanisms of immunotoxicity/immunopharmacology using appropriate technologies, including flow cytometry, specialized imaging, differentiated stem cell culture models, complex and long-term primary cell culture models, biochemical assays, and multiplex immunoassay systems.
- Interpret and communicate complex data sets to deliver timely and decisional quality insights to inform decision-making processes throughout program progression from target characterization to the clinic.
- Serve on drug discovery & development teams as an active scientific matrix leader providing immunotoxicology expertise for our expanding portfolio, while also being directly involved in matrix leadership and mentorship to our technologically advanced La Jolla, California-based laboratory.
- Interfacing with CRO partners for collaborating on immunotoxicology analyses on in vivo toxicology studies, addressing health authority queries on cross-functional teams, participating in issue resolution teams, and managing laboratory strategy and operations as well as data integrity initiatives.
- Expand breadth of knowledge and external influence by maintaining professional memberships in external organizations (eg. SOT, ACT, BioSafe, HESI Immunosafety Committee) and attend and/or participate in scientific meetings to increase visibility of self and J&J Innovative Medicine, through external presentations and publications.
- Support career development and immunology learnings across the organization.