PhD student in Endodermal Organ Biology

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

In Roche’s Pharmaceutical Research and Early Development organization (pRED) , we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

The Institute of Human Biology (IHB) is a newly established research center in Basel, Switzerland, dedicated to advancing human biology through the use of human model systems for translational research. Our dynamic and interdisciplinary environment fosters collaboration among biologists, engineers, and data scientists, bridging the gap between academic and pharmaceutical research. Closely associated with Roche’s Pharmaceutical Research and Early Development (pRED), we partner with leading academic institutions both locally and globally to address grand challenges with bold, innovative science.

Your Impact

We are seeking highly motivated students to apply for PhD positions in the newly established team of ‘Patho-biology of Endodermal Organs’ at the IHB. The PhD students will be supported to conduct ambitious exploratory research focused on homeostasis and disease of the adult liver, lung or pancreas, using organoid models.

You will be able to access cutting-edge technologies developed at the IHB such as advanced bioengineered models, single-cell genomics and high-content imaging.

Additionally, translational opportunities may arise from your research and you are encouraged and supported to translate models and findings to the wider pRED community.

Location

Basel, Switzerland

Your Profile

We are looking for highly motivated, creative and independent students who are excited about working in a dynamic team aiming at pushing scientific frontiers.

You have completed a Masters degree in cell biology or a related field, and are interested in working on homeostasis and disease mechanisms in the liver, lung or pancreas.

Prior experience with organoid models is an advantage.

To be considered your application needs to include:

• A cover letter

• A CV (including a list of relevant publications)

• The names of three references

IHB Fast Facts

• IHB website: https://institutehumanbiology.com

• IHB Director: Hans Clevers

• CoDirectors: Marianne Manchester, Matthias Lutolf, Daniele Soroldoni

• Planned Size: 250 researchers

• IHB platforms and expertise: Single-cell genomics, Microtechnologies, bioengineering, High-throughput imaging, CRISPR-gene editing, Biobanking, Automation, Applied translation support

• Core facilities: Fluorescent microscopy, Genomics and high-throughput sequencing, Flow cytometry and cell sorting, Proteomics/Metabolomics, Information technology

• PhD program: Department of Biosystems Science and Engineering, ETH Zürich

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more .

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.