Vaccine Manufacturing Scientist

Vaccine Manufacturing Scientist Description
Function
Vaccine Manufacturing Scientist Location / Contact
AC Immune SA, EPFL Innovation Park, Building B, 1015 Lausanne E-Mail schreiben Percentage
100 %
Reporting Line
DP Manufacturing Science and Technology Group Leader Overview

• AC Immune is a clinical stage Swiss biotech company focused on the development of innovative therapeutics and diagnostics for Alzheimer's and other neurodegenerative diseases
• 150+ Employees, 20+ nationalities, IPO in 2016, listed on NASDAQ
• AC Immune SA is a progressive, equal opportunity employer

Job description
The Liposome Vaccine Manufacturing Scientist will be responsible for the in-house process development and manufacturing of liposomal vaccines for subsequent use in research and preclinical studies. The candidate will manage the in-house manufacturing facility, supervise the in-house activities and will drive the implementation of innovative technologies aimed at enhancing the SupraAntigen platform. Key responsibilities

• Define systematic and scientifically driven studies aimed at optimizing manufacturing processes and scale-up
• Introduce innovative technologies and approaches for the manufacturing of liposomal vaccines
• Ensure mirroring of manufacturing processes between AC Immune and

CMOs (scale-down level)
- Plan and supervise in-house manufacturing activities (MFG Technicians) to ensure timely delivery in liaison with ADQC team and CMC project management

• Management of data and documentation in the ELN and/or Veeva systems (experimental protocols and reports, batch records, SOP/WI)
• Responsible for preparation of in-house equipment maintenance plans
• Responsible for the yearly budget related to maintenance, CAPEX, materials and consumables of in-house manufacturing facility
• Responsible for the Lab organization and house-keeping

(environmental control), and related safety aspects. Liaison with Facility Management and EHS functions. Qualifications
Qualifications:

• PhD in Material Sciences or Life sciences
• Has at least 5 years of experience with nano-formulations (liposomes, drug substance and/or drug product manufacturing)
• Has demonstrated ability to analyze data and generate reports
• Prior process development (DoE, QbD principles, scale-up) experience is a plus Personal features include:
  
• Strong scientific acumen
  
• Ability to build and execute experimental plans diligently and to address issues autonomously
• Ability to integrate and learn fast
• Strong interpersonal skills for efficient collaboration with all colleagues
• Fluency in spoken and written English